George Kittle, Deebo Samuel, and Christian McCaffrey have all scored multiple touchdowns in the 49ers’ recent visits to SoFi Stadium.

San Francisco 49ers quarterback Brock Purdy will be tested in the coming weeks with the absence of key offensive weapons.

It's only Week 3, but both the 49ers and Rams are dealing with several key injuries entering Sunday's game. For San Francisco ...

Brock Purdy plays much better with Deebo Samuel than without him. That's a fact. This Sunday, Purdy and the 49ers will have ...

Head coach Kyle Shanahan shared the final injury report ahead of the 49ers Week 3 matchup and discussed the team's ...

San Francisco 49ers head coach Kyle Shanahan joined Bay Area radio station KNBR on Thursday to provide an update on two ...

Brock Purdy has faced the Vikings twice in his career. In both games, he turned the ball over twice, led the 49ers to just 17 ...

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Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

The 49ers confront a critical challenge as pressure mounts on quarterback Brock Purdy, jeopardizing their championship hopes.

Fantasy football analyst Matt Harmon provides his weekly viewing guide, discussing which matchups to binge, stream and skip in Week 3.