Michigan will help college football fans adapt to the demise of the Pac-12. The 11th-ranked Trojans and No. 18 Wolverines played a regular-season game for the first time in 66 years and it was an instant Big Ten classic.

Utah stayed unbeaten with a 22-19 win at Oklahoma State, the first Big 12 matchup for Utes as one of the league's newcomers. And Kyle Whittingham's team did it without quarterback Cameron Rising, who was a late scratch in Stillwater.

There are highs and lows every week in college football. The winners and losers for Week 4 start with Southern California's loss to Michigan.

The Wolverines grinded out a win over the Trojans, plus the rest of the weekend’s most notable winners and losers so far.

The Big Ten College Countdown crew breaks down Michigan's close win over USC, including the play of Alex Orji, the Wolverines' emphasis on the run game, and USC's introduction to the Big Ten.

Run the ball and play defense. And the Wolverines did just enough of both to knock off USC 27-24 in the Trojans’ first-ever Big Ten game. Michigan quarterback Alex Orji, making his first career start,

No. 18 Michigan inflicted a pair of significant blows in the first half against No. 11 USC on Saturday, taking a 14-3 lead into the break behind stingy defense and explosiveness in its run game. Kalel Mullings busted a 53-yard touchdown run on the Wolverines' third possession to open the scoring after the teams traded early punts.